Pre-Conception Recessive Mutated Gene Test

The Pre-Conception/Pre-Natal Recessive Mutated Gene Test is quickly becoming a standard-of-care to prevent the birth of children with certain incurable diseases. If BOTH parents are carriers of the same mutated gene, the child will have a 25% risk of developing that genetic disorder.

Most laboratories test for approximately 400 mutations. Our testing laboratory uses the most sophisticated technology available and tests for over 3,000 mutations to identify 62 variations of 24 incurable diseases . The ratio of mutations tested to diseases identified is an integral part of why our test is so very accurate. The more accurate the results, the less likelihood of giving birth to a child with a genetic disorder.  Nearly all PPO insurances will pay for this test.

What is the Carrier Screening test?

Carrier Screening is a simple mouthwash rinse non-invasive genetic mutation test that can identify carriers for multiple prevalent and devastating hereditary diseases that can be passed down unknowingly to children. This includes diseases such as: Cystic Fibrosis-Sickle Cell Anemia-Fanconi Anemia -Bloom Syndrome-Spinal Muscular Atrophy-Gaucher Disease - Familial Dysautonomia-Tay-Sachs and many others...

Why is Carrier Screening important?

About 80% of all recessive diseases occur in families with no known family history of a disease and therefore have no indicator that they are carrying a disease causing mutation. In populations where carrier testing is prevalent, incidence of disease had dropped by as much as 90%.

Who may be a Carrier of a Hereditary Disease?

Anyone can be a carrier. Studies have shown that the likelihood of being a carrier for an inherited genetic disease can be as high as 1 in 4 for certain populations.

Who is Eligible for Carrier Screening?

Carrier Screening for inherited genetic condition is recommended by American College of OB/GYN and American College of Medical Genetics for ALL patients of reproductive age.

Does Insurance Cover Carrier Screening?

Most PPO insurances cover Carrier Testing for All people of reproductive ages 18 to 45 since it is much more cost effective to prevent these diseases than the lifetime treatment of someone born with an incurable disease.

What is the turn-around time and how are results Reported?

The results are placed in the doctor’s portal, usually in less than 30 days. The doctor also has the option to have the report faxed.

 

Genetic Cancer Gene Testing

Because genetic pre-disposition is recognized as a definite increased risk factor for developing cancer, genetic testing is becoming increasingly used to detect those people who may be at risk for many malignancies. A non-invasive test  can identify those people who are at high risk of developing Breast, Colo-rectal, Pancreatic, Prostate, Ovarian, Gastric, Melanoma and Endometrial cancer.

Testing positive for a particular cancer marker dramatically increases that persons risk of developing that cancer. For example, as opposed to the general population breast cancer risk goes from around 12% to over 85%. Colorectal goes from about 5% to almost 100%.

Why would someone want to know this information? Because if they know they are genetically pre-disposed to any of these eight cancers, they can reduce the risk, or even PREVENT the cancer from occurring!  At the very least they can go for more often observation so as to detect at the earliest stages,   Does early detection really make a difference?  The survival rate for 1st stage diagnosis of breast cancer is 99% as opposed to 22% for 4th stage. Prostate cancer survival rates are about the same. Even pancreatic cancer goes from 13% to 1%.       

 

Pharmacogenomic (PGx) Testing 

One of the primary causes of malpractice legal actions against doctors is misdiagnosis and prescribing of inappropriate medication. Thousands of doctors across the country are dramatically improving the healthcare of their patients while reducing their exposure to lawsuits with the PGx test.  Increasing the efficacy of medications, decreasing the potential for adverse drug reactions(ADRs) and reducing the number of prescribed medications top the list of key advantages.  With our lab, you have access to one the most advanced and comprehensive PGx tests in the country.

PGx is a noninvasive test that based on a persons DNA will determine whether that particular patient metabolizes medications at a slow, rapid or normal rate. Furthermore it will advise which medications under a specific class will be most effective for that patient. Additionally if that patient is taking more than one medication the test will indicate what combination will provide the highest efficacy with the lowest side effects. Rather than prescribing based only on symptoms, and the "trial and error" approach, now the doctor can prescribe based on knowing what medications, dosage strength and dosage frequency will be most effective for that person.

The FDA has posted 200 Black Box Warnings where manufacturers recommend pharmacogenomics testing prior to or soon after initiation of therapy. Of those, over 100 drugs require pharmacogenetic testing prior to prescribing, or it is highly recommended.  You have always diagnosed with all of the science available; now you can treat your patients with cutting edge science as well. With the PGxOne™ Plus test, the results are easy to decipher and our lab pharmacy representatives are available for consultation so you can prescribe with the Right Information for the Right Drug, in the Right Dose, for each patient.

But a PGx test goes even further in setting protocol's to keep patients healthy. For example some people do not have the enzyme which  enables them to convert folate and foloic acid, each a form of vitamin B9, into a usable form 5-MTHF. If they cannot metabolize folate and folic acid properly they are at risk of cardiovascular disease, stroke, macular degeneration, Alzheimer's, hearing loss and cancer. All of this can be addressed by diet and nutritional supplements...but only if you and your patient know!